While studies continue praising the many benefits of omega-3s, it's important to understand that omega-3s are NOT all the same.
Did you know that the capsules of different brands of omega-3 can have varying amounts of actual omega-3 in them? You will find it interesting to compare the amount of EPA and DHA in your fish oil with ours. Kind of makes you wonder why there is so much filler in lots of the Omega-3 products out there...and more importantly, it could explain why you may not be getting the results that are possible with a high purity Omega-3 product. And be careful; if you just take more of a poor quality Omega-3 you'll also be taking the additional filler that comes along with it!
WINOmeg3complex™ is an ultra-purified, pharmaceutical-grade omega-3 product with a high EPA concentration for maximum support of healthy and flexible joints, heart health, brain health, skin health, mood, and more. That's a lot of benefits in one product!
Achieve optimal health with WINOmeg3complex™. Our high concentration formula contains a desirable balance of essential fatty acids and undergoes an enzyme process and two molecular distillations to ensure the removal of PCBs, dioxins, mercury and other heavy metals.
This product is gluten free.Part of the Physicians' Health & Diet® program!
The American Heart Association recognizes the importance of Omega-3's in promoting and protecting cardiac health and fitness.
For best results, drink plenty of water. Results may vary by individual. 30 Day Money-Back Guarantee!
Q: How long does it take to see results?
Each person has a different individual response and results can be seen in as little as two days, or can take weeks. You may continue to see improvements in your body* over a period of time as your body is replenished with omega-3s in WINOmeg3complex.
Q: How long does a bottle last?
Based on the recommended serving of 2 capsules a day for healthy adults, a bottle of WINOmeg3complex should last 30 days.
Q: How is WINOmeg3complex different from other fish oils on the market?
WINOmeg3complex has several differences from ordinary fish oil:
WINOmeg3complex's highly concentrated fish oil is produced under pharmaceutical conditions in a GMP approved facility, and undergoes multiple molecular distillations and a patented enzyme process to remove potential heavy metals and toxins, and to obtain an oil with more than 85% omega-3 fatty acids. Compare this to most products on the market that are 30%-35% concentrated, and even to most of the pharmaceutical grade fish oils with concentrations of 60%-65%, and you can see how it would take many more capsules daily to equal the amount of omega-3 fatty acids found in one serving of WINOmeg3complex. (Data available from WIN upon request.)
WINOmeg3complex's highly concentrated fish oil is one of the freshest products on the market, with no fishy aftertaste. WINOmeg3complex is manufactured in a nitrogen environment to prevent the oxidation that occurs when omega-3 is exposed to oxygen in the air. This manufacturing process results in low peroxide values (freshness values) that are approximately six times lower than the Norwegian Medicinal Standard and the European Pharmacopoeia Standard limits. The lower the peroxide value, the fresher the oil. Compare WINOmeg3complex to most fish oil products on the market that leave a fishy aftertaste which can linger over several hours.
WINOmeg3complex's highly concentrated fish oil contains a minimum of 60% EPA, with a 3.3 to 1 ratio of EPA to DHA. After the first three years of life, DHA is only needed in small amounts to maintain health. back to top
Q: How do I know if I need to take an omega-3 supplement?
The omega-3 fatty acids found in WINOmeg3complex are beneficial to everyone.* The omega-3 nutrients in WINOmeg3complex are well established in the scientific community. Both the American Heart Association and the World Health Organization recognize the importance of omega-3s.
Q: Why is an extra daily intake of omega-3 necessary?
The body cannot generate the omega-3 fatty acids EPA and DHA by itself. It needs to derive the materials necessary to produce EPA and DHA from a diet that is rich in omega-3. Unfortunately, a typical Western diet lacks omega-3 fatty acids. That has not always been the case. Historically, our current diet contains approximately 10-20 times more omega-6 than omega-3. Commonly used vegetable oils and processed foods consist almost exclusively of omega-6 fatty acids and hardly any omega-3 fatty acids. Therefore, taking EPA and DHA supplements is a conscious choice you can make to achieve a balance between omega-6 and omega-3 fatty acids.
Q: What general health benefits are associated with omega-3 fatty acids?
Every cell in the body requires omega-3 fatty acids to form normally functioning cell membranes — the envelope surrounding every cell. In addition to this role in the cell membranes, the omega-3 fatty acids are converted into a class of compounds called eicosanoids (i.e. prostaglandins).
Q: Can’t I just eat more fish?
Yes, eating more fish would be a healthy choice for most people. However, many wild species of large predatory fish (e.g. fish that eat other fish) are contaminated with methyl mercury, lead, PCBs and other environmental contaminants. Also, farm raised fish fed contaminated feed have higher concentrations of PCBs. As a result, the FDA has formally warned pregnant and lactating women, and children, to avoid eating swordfish, shark, king mackerel and tilefish. Additionally, in July 2002 the FDA’s Food Advisory Panel (pdf file) recommended that women consume no more than one 6-ounce can of tuna per week. With concerns about heavy metals and other toxins in fish, understandably people are concerned about consuming significant amounts of seafood. And yet, by not consuming fish, we all miss the opportunity to obtain important omega-3 fats in the diet. Ideally, smaller, shorter-lived, non-predatory fish (anchovies, sardines, herring) would be a better choice for people concerned about their health. However, if these types of fish are not a mainstay of your diet, supplementation with a high quality omega-3 product may be the answer.*
Q: Is WINOmeg3complex tested for mercury?
Each batch of WINOmeg3complex is tested for dioxins, PCB’s, mercury, and other metals. WINOmeg3complex test results meet or exceed the purity standards of California Proposition 65 and the Council for Responsible Nutrition.
Q: Does WINOmeg3complex contain flaxseed oil?
No. WINOmeg3complex does not contain any flaxseed oil. WINOmeg3complex contains a minimum of 85% omega-3 essential fatty acids derived from fish. The fish oil is distilled from very small fish that occupy the lowest level of the food chain (anchovies, sardines, herring) because they are considered to be a better choice for raw materials as they are naturally higher in omega-3 fatty acids and naturally contain lower levels of environmental contaminants than fisher higher on the food chain (like tuna, shark, marlin), as they swim in the cold Artic waters off the southern tip of South America. EPA and DHA are produced in phytoplankton. Each capsule of WINOmeg3complex contains 60% EPA and a maximum of 20% DHA. Flaxseed oil is from a plant source.
Q: Isn’t flaxseed a good source of omega-3?
Omega-3 fatty acids fall into two categories: plant-derived (flaxseed oil yielding alpha-linolenic acid or ALA) or marine-derived (fish oil yielding both EPA and DHA). The human body converts ALA with great difficulty into EPA and DHA. The conversion rate is slow and inefficient (between one and five per cent), and can be inhibited by various conditions such as a diet high in linolenic acid (omega-6), trans fatty acids such as fast foods and baked goods, alcohol intake, certain health conditions, and vitamin and mineral deficiencies (B3, B6, C, zinc, magnesium). It is only the omega-3 EPA and DHA that have health benefits. This is not to say flaxseed oil is bad. It is just not a very good option compared to fish oil because of the very inefficient ALA to EPA and DHA conversion that takes place. Therefore, you may need to consume considerably more flaxseed oil than fish oil. Fish oil, on the other hand, is a direct source of EPA and DHA and does not have to be converted by the body to provide us with the EPA and DHA. The fish convert them for us.
Q: How much DHA is in each capsule and serving size?
Each WINOmeg3complex capsule contains approximately 160 milligrams of DHA.*. One serving size of WINOmeg3complex (two capsules) contains approximately 320 milligrams of DHA*
*EPA and DHA are naturally occurring constituents of omega-3; thus product and content varies slightly with each batch.
Q: What is DHA?
DHA is an omega-3 long-chain fatty acid that is the primary building block of the brain and retina. The brain is 60% fat, and DHA is the most abundant fatty acid in the brain, comprising 25% - 35%. DHA is found in even greater concentrations, 50%-60% in the retina.
Q: How much WINOmeg3complex should people take?
As with any supplement, you should check with your healthcare provider requiring the appropriate serving. However, for overall health,* 2 capsules per day is generally adequate.
Q: How much EPA is in each capsule and serving size?
Each WINOmeg3complex capsule contains approximately 540 milligrams of EPA*. A recommended serving size of WINOmeg3complex contains approximately 1080 milligrams of EPA*
* EPA and DHA are natural substances, and thus content varies slightly with each batch.
Q: What is EPA?
EPA is a member of the omega-3 fatty acid family that is found in fish oils of liver, herring, mackerel, salmon, and sardines. It is also found in breast milk. Research has taught us that a lack of EPA weakens the body’s immune system.
Q: What does the term “pharmaceutical grade fish oil” mean?
The term “pharmaceutical grade” refers to a set of specifications that include providing at least 60% concentration of the most active long-chain omega-3 fatty acids (EPA and DHA) in the oil after processing and includes quality control steps to ensure the product is free from lipid peroxides, heavy metals, environmental contaminants, and other harmful compounds. The ratio of omega-3 fatty acids to arachidonic acid (AA) must be greater than 50 to 1. It must also contain optimal amount of tocopherols as a preservative.
Q: What is the difference between “pharmaceutical grade" and “produced under pharmaceutical grade conditions?”
“Pharmaceutical grade” is a classification of the potency and purity of the product. “Produced under pharmaceutical conditions” means that the facility where the product is produced and packaged is supervised and under the authority of a government agency that oversees companies that produce prescription medication in a sterile environment and also with drug GMPs.
Q: Ethyl Ester (EE) vs. Triglyceride (TG) fish oils – how do they compare?
It is true that most ordinary fish oil supplements have EPA and DHA in the triglyceride form. The process of converting TGs to EEs is necessary in the production of fish oil concentrates to purify the oil. However, once this molecular distillation process is completed, there is an option to leave the fatty acids in free form, attached to an ethyl alcohol backbone, or to reattach them to a glycerol backbone (triglyceride). It is this one final step known as “re-esterification” that differentiates between WIN’s two omega supplements.
WINOmeg3complex is available as a highly concentrated molecularly distilled omega-3 ethyl ester in the United States and many European markets. Currently, Australia and Germany only permit the natural triglyceride-form of fish oil, so for those countries WINOmeg3complex is converted back to a triglyceride.
Q: But isn’t there a difference in the biological availability of EPA and DHA as triglycerides and as ethyl ester?
EPA and DHA ethyl esters have been examined in clinical studies for 15 years. In 1991, Nordoy and Connor demonstrated that the body will absorb ethyl esters as well, or even better, than EPA and DHA triglycerides (Publication in the American Journal of Clinical Nutrition). Most studies on EPA and DHA recently have been conducted with omega-3 ethyl esters. They have proved effective. They have been approved safe.
Q: What are the standards for fish oil?
Currently, no quality standards exist for fish oil in the United States. The Council for Responsible Nutrition (CRN), a trade organization for supplement suppliers and manufacturers, has recently developed U.S. voluntary guidelines (pdf file). Some fish oil supplement manufacturers adhere to European fish oil standards, such as the Norwegian Medicinal Standard and the European Pharmacopoeia Standard (pdf file). European standards are higher than the current voluntary and proposed standards set by the CRN. For example, while the CRN encourages dioxin levels to be measured in parts per million, Euro standards are set in parts per trillion. WINOmeg3complex is manufactured according to the stringent European Pharmacopoeia and Norwegian Medicinal Standard requirements and surpasses all international standards for freshness and purity. In addition, WINOmeg3complex meets or exceeds California Proposition 65 and the CRN voluntary monograph.
Q: How is WINOmeg3complex tested for the percentage of omega-3?
There are two different testing methods used to analyze the fatty acid content of WINOmeg3complex: Area Percent and Weight Percent. The Area Percent method calculates EPA and DHA as a fraction of total fatty acids in the oil. This method excludes non-fatty acid components (e.g.: the glycerol backbone and unsaponifiable matter in the oil) which accounts for 5%-15% of the total. It is based on the sum of the identified fatty acids equaling 100% and was developed by the European Pharmacopoeia. The Weight Percent method, also known as mg/g, takes into account the weight of the fatty acids plus glycerol backbone and unsaponifiable matter when calculating the EPA/DHA content. The weight percent of each fatty acid is compared to the overall weight of the oil (mg/g). This method is used by regulatory agencies and consumer groups, like FDA and consumerlabs.com, to analyze the fatty acid content of the oil. Both of these testing methods guarantee truth in labeling for omega-3 ethyl esters found in WINOmeg3complex.
Q: Are there any side effects?
There are no drug-like side effects to WINOmeg3complex. Rarely, a person may have some temporary GI distress taking WINOmeg3complex, but this can be minimized by taking WINOmeg3complex with food, or by dividing the serving. WIN has never received a report of a serious adverse event from our omega-3 supplement.
Q: Is WINOmeg3complex a natural product?
WINOmeg3complex is a safe, natural, highly purified form of omega-3 essential nutrients in marine fish oil. The only adaptation which takes place is the conversion of triglycerides into ethyl esters. This is an environmentally-friendly procedure which assures the quality of multiple unsaturated fatty acids such as EPA and DHA.
Q: Who needs a high quality EPA supplement?
WINOmeg3complex is an ideal supplement for those who need a maximum amount of EPA. WINOmeg3complex contains three times more EPA than the average fish oil supplement that is on the market today.†
† Compared to Health Food Grade fish oils such as TwinLab® Omega-3 Fish Oil, which only contains 390 mg of omega-3 fatty acids per serving vs. WINOmeg3complex™ which contains 1400 mg per serving.
Q: What is the suggested serving?
For optimal absorption, it is best to take WINOmeg3complex capsules with a full meal. It is also recommended that you take antioxidants daily. For the best results, it is advisable that you decrease your consumption of omega-6 containing seed oils such as corn oil, sunflower oil, or safflower oil and decrease your saturated and trans fatty acids found in processed and fast foods (including cereals, baked foods, fried, foods, margarine, and others). (Canola oil and olive oil are recommended cooking oils.)
To determine the amount of WINOmeg3complex that works best for you, gradually increase the number of capsules up to 6 capsules per day, or as directed by your healthcare provider. You may take all the capsules with one meal or split them up with meals. It is important to take WINOmeg3complex on a regular daily basis. Individuals vary in their time to achieve a response. Some people feel significantly better after several days, although most individuals take several weeks to a month to experience the health benefits* from WINOmeg3complex.
All matters of health should be supervised by a health care professional. If you are on medications, you should check with your doctor before starting any dietary supplement.
Q: Is omega-3 recommended by any health authorities?
The United States Department of Health and Nutritional Services, the National Institute of Health the American Heart Association, the American Dietetic Association, the Life Sciences Research Offices of the Federation of Societies of Experimental Biology and the Council for Responsible Nutrition have all agreed that the daily intake of omega-3 should be increased. The World Health Organization recommends that all adults increase their intake of omega-3.
Q: What if I can’t swallow a capsule?
WINOmeg3complex is manufactured as a soft gel cap. However, if you have difficulty swallowing oils/gel caps, piercing the gel cap with a sterilized pin and squeezing the oil into a liquid (juice, smoothie, etc) or pudding is fine. This will not compromise the effectiveness of WINOmeg3complex.
Q: Can I take WINOmeg3complex if I am allergic to fish?
Most fish allergies would not be activated by taking WINOmeg3complex since almost everything is removed except for the omega-3 fatty acids, which are beneficial for everyone.* However, since we do not have information on what you are specifically allergic to, it is best to check with your healthcare provider before taking any new medicine or supplements.
Q: I heard that fish oil and EPA can cause bleeding, is this true?
Aspirin (or Motrin, Advil, and the other non-steroidal anti-inflammatory drugs (NSAIDs)) reduce the stickiness of blood platelets, which are necessary for blood clotting. While Omeg3complex has been shown to reduce platelet stickiness, there are no established causes of excessive bleeding during omega-3 fatty acid treatment. However, if you have a bleeding disorder, or if you are receiving Rx anticoagulants, such as Coumadin (warfarin), check with your healthcare provider for using WINOmeg3complex.
Q: Is it true that antioxidants help omega-3 work better?
Antioxidants, such as Vitamins E and C, may prevent omega-3 fatty acid oxidation in the body. This prevents the formation of so-called lipid peroxides, which are highly reactive and possibly damaging. This could possible help maintain higher levels of omega-3s. These vitamins are harmless, and appear to have their own health benefits*, when used as directed.
Q: Why are fish so contaminated?
Sadly, eating most fresh fish, whether from the ocean, lakes and streams, or farm-raised is no longer recommended. The problem with fish is that nearly all fish are contaminated with mercury. Over half the US burns coal to generate electricity, and over 80,000 lbs of mercury is dumped into the oceans every year. However, even if you choose salmon, tuna or swordfish, they often have unhealthy levels of chemicals such as dioxins, PCBs, pesticides, and dangerous amounts of metals such as mercury.
People used to think farmed fish were safe (95% of salmon purchased in US is farm-raised), but it turns out they have as much or more mercury and PCBs as wild fish. For salmon, the increased mercury and chemicals occur because the salmon are carnivorous and are fed pellets containing mercury from wild fish. Eating fish in low doses is OK—one or two meals a week is enough not to raise your mercury levels much. For nursing mothers and children, it may be best to avoid fish altogether. Some fish have little or no contamination. Little fish, like mackerel, sardines, and herring, do not live a long time and are non-predatory, are cleaner and contain less or no contaminants. Large predatory fish, like tuna, tend to be the most contaminated.
According to studies conducted by an independent laboratory, AXYS Analytical Services, Ltd of Sidney, B.C., results concluded fish oil capsules contain only a fraction of the PCBs found in fresh farmed fish. The results stated that a person would need to consume 312 fish oil capsules to be exposed to the amount of PCBs found in a single serving of farmed salmon. Even the cleanest serving of farmed fish had as much PCB as 63 fish oil capsules!
Q: Is there research on omega-3?
There has been a considerable amount of research on the omega-3 fatty acids EPA and DHA found in WINOmeg3complex. As of 2003, more than 20,000 scientific articles and reports have been published on the various effects of omega-3, and the story goes on. Much of today’s research revolves around the value of marine omega-3 fatty acids in the relation to the physical, mental, and intellectual development of premature infants*, though WIN makes no such claims.
Q: WINOmeg3complex and medications.
WINOmeg3complex can be taken with most medications. However, each individual is unique and it is important that you speak to your health care provider regarding any food supplement when you are on medications. By FDA law, we are unable to provide medical advice regarding the use of WINOmeg3complex. All questions regarding use of WINOmeg3complex and medical health problems should be discussed with your health care provider.
Q: What is the shelf life of WINOmeg3complex?
WINOmeg3complex contains a protective dose of mixed tocophenols (antioxidants) that keep the omega-3 fatty acids in a biologically active state and limits the risk of peroxidation. This gives WINOmeg3complex a shelf life of 2 years, when kept in a dry place at a temperature between 15 and 25 C. Note: exposure of the product to light and high temperatures reduces its shelf life and may damage the soft gel capsules.
Q: Why is WINOmeg3complex better than cod liver oil?
WINOmeg3complex contains a minimum of 85% omega-3 fatty acids, with a high concentration of EPA for its maximum natural anti-inflammatory benefit.* Cod liver oil has the least amount of omega-3 fatty acids (20%-24%) with little or no EPA and DHA (biological forms of omega-3 fatty acids used by the body), the highest levels of contaminants (heavy metals like mercury and lead, PCBs, DDT, flame retardants); in addition to the fact that higher doses of cod liver oil are not recommended in higher doses due to high levels of Vitamin A found in this form.
Q: Can I take more, or what if I need more?
If you do not see results in two to three weeks gradually increase your amount. If you have further questions, you may check with your health provider.
Q: Is there any cholesterol in WINOmeg3complex?
There is no cholesterol in WINOmeg3complex.
Q: I’ve heard that a lot of fish oil supplements have so much saturated fat that it outweighs the benefit of taking omega-3. How much saturated fat is in WINOmeg3complex?
Yes, that’s correct. Ordinary fish oil supplements often contain as much as much as 40% saturated fat. But one serving of WINOmeg3complex (2 soft gel capsules) contains less than 1g saturated fat, making it one of the purest products on the market.
Q: What should I look for when purchasing fish oil?
Manufacturing: Investigate the manufacturing process. How is the fish oil manufactured and what are the manufacturing standards?
Smell: Does the fish oil smell fishy? If it smells fishy, the fish oil has most likely been exposed to oxygen and is becoming rancid.
Taste: Does the fish oil taste fishy? The freshest fish oils should not taste fishy.
Desirable characteristics of an omega-3 fatty acid supplement are: highest concentration of omega-3 fatty acids, highest concentration of EPA per capsule, high ratio of EPA to DHA, low omega-6 fatty acid and saturated fat concentration, pharmaceutical grade purity, Good Manufacturing Practices (GMP), color and smell of oil, molecular distillation, winterization, manufactured and encapsulated under nitrogen, peroxide value less than 5 at time of manufacture, source of the fish oil (including the type of fish used and location of catch), low cholesterol concentration, no cod liver oil, and presence of tocopherols (Vitamin E) in the encapsulated oil as antioxidants.
Q: Unique strengths of WINOmeg3complex in a nutshell.
Choosing an omega-3 supplement can be very confusing. There are many products to choose from – with different features, quality, and prices. A high quality pharmaceutical grade omega-3 supplement should have the characteristics listed below.
WINOmeg3complex is a omega-3 fatty acid supplement that has them all:
Pharmaceutical grade: WINOmeg3complex is manufactured in accordance with Good Manufacturing Practices (GMP). WIN’s supplier has been certified by the Norwegian Medicines Agency for the production of pharmaceutical substances.
Exceptional Raw Materials: WINOmeg3complex is manufactured exclusively from fish (anchovies, herring, and sardines) harvested from the cold Arctic waters off the western coast of South America. These non-predatory short-lived fish are naturally high in the omega-3 fatty acids EPA and DHA.
Exceptional Purity: The purification process that gives WINOmeg3complex its exceptionally high concentration (>85%) of omega-3 ethyl esters also eliminates all the pollutants currently found in fish, whether farmed or wild. Quantities of heavy metals (such as iron, arsenic, cadmium, lead, mercury and copper) and other pollutants (such as DDE, DDT and HCB) are certified to below detectable levels. In particular, WINOmeg3complex oils show no detectable PCB’s when tested down to 10ppt, or more than twenty times the standard set by the Food and Drug Administration (FDA)(2000ug/kg), and more than ten times lower than the WHO standard. Similarly, the dioxin levels are below 2 picograms(pg) teq/g, in line with European regulations.
Exceptional Freshness: Freshness, which ensures product quality and biological efficacy, may be the single most important quality of fish oil. WINOmeg3complex is manufactured in a nitrogen environment and is continually exposed to nitrogen throughout the entire process to prevent the oxidation that occurs when omega-3 oil is exposed to oxygen in the air. WINOmeg3complex’s manufacturing process delivers peroxide values (indicators of freshness) down to absolute 0.0mEq/kq, with an average of 1.6mEq/kq or approximately six times below the Norwegian Medical Standard and the European Pharmacopoeia Standard limits. The lower the peroxide value, the fresher the oil.
Exceptional Quality: When we talk about quality in WINOmeg3complex, we do not limit ourselves to the product itself. For us, quality starts with a spotless product and ends when we have a satisfied consumer. We pride ourselves on the fact that our quality is consistent with respect to important parameters such as purity, oxidation, color, taste and smell – the same high quality every time! Having a fully fledged pharmaceutically licensed supplier produce, test, document and evaluate WINOmeg3complex, rubs off and lifts the bar for quality omega-3 supplements in the marketplace.
Q: Do you have any reading material you might suggest about the benefits of adding omega-3s to my diet or my children’s diet?
The omega-3 Diet; The Lifesaving Nutritional Program Based on the Diet of the Island of Crete; by Artemis P. Simopoulos, M.D., and Jo Robinson
How To Get Kids To Eat Great & Love It!; Giving Your Children the Gift of health with Good Nutrition and Supplementation Now and Long into the New Millennium; by Christine Wood, M.D.
Fatty acids are the building blocks of dietary fats. The human body stores such dietary fats mainly in the form of triglycerides. Triglycerides containing omega-3 fatty acids are mainly found in fish.
Essential fatty acids
The bulk of fat contained in our diet are the triglycerides. The triglycerides contain three fatty acids, saturated and the two unsaturated fatty acids, DHA and EPA. Fats with a high content of saturated fatty acids are solid at room temperature, butter and fat from red meat, for example. Fats with a high content of unsaturated fatty acids are soft or liquid at room temperature, for instance, soft margarine, plant oils and fish oil.
The terms saturated and unsaturated refer to the chemical structure of the fatty acids. Unsaturated fatty acids have one or several double bonds. In omega-3 fatty acids, the double bonds start at the third carbon atom counted from the Omega end. In omega-6 fatty acids, the double bonds start at the sixth carbon atom.
Although animals and humans are not able to produce them naturally, polyunsaturated fatty acids are essential for normal life functions. They are therefore characterized as essential fatty acids. Polyunsaturated fatty acids are produced by various plants. They reach man through the food chain, either directly through the consumption of fruit and vegetables, or by eating the flesh or eggs of animals, birds or fish that have eaten plants containing the polyunsaturated fatty acids.
Essential polyunsaturated fatty acids can be classified as belonging to one of two "families", the omega-6 family or the omega-3 family. Fatty acids belonging to these two families differ not only in their chemistry, but also in their natural occurrence and biological function. Omega-6 fatty acids are typical of the polyunsaturated fatty acids found in terrestrial plants and they will be present in that part of the food chain. Omega-6 oils are found in cooking oils such as corn oil and soybean oil. Omega-3, on the other hand, is produced by marine plankton and is heavily represented in the marine food chain. The most important source is fat fish.
The nutritional gap
While the recommended daily intake of marine omega-3 fatty acids should be in the range 0.6 - 1 gram per day, a "normal" diet in the Western world only satisfies about 10-15% of this requirement. The remaining requirement, the "nutritional gap", can be covered by increasing one's consumption of fatty fish or by using suitable dietary supplements.
"The dietary ratio of Omega-6 to Omega-3 should be from 1:1 to 4:1."
Indeed, an imbalance in this ratio causes inflammation—which can be discussed in terms of compromised joint health, heart health, and the immune system.* The biological importance of polyunsaturated fatty acids Polyunsaturated fatty acids play a central role in the cell membrane, the "wall" surrounding all living cells. The composition and structure of the cell membrane is very important for maintaining normal cell function. All nutrients and waste substances have to be transported through the cell membrane. The same happens to biological products produced by the cells, i.e. hormones or other substances used by other cells in the body.
Given a daily energy intake of 2500 kcal, people should eat about 0.6 - 1 g of EPA and DHA, and at least 0.2 - 0.3 g of it should be DHA (Marine Omega 3 Fatty Acids)
Another important function of polyunsaturated fatty acids containing 20 carbon atoms (C20) and particularly arachidonic acid (omega-6) and eicosapentaenoic acid (omega-3) is that they can be converted to locally functioning transmitter substances. Among these transmitter substances, prostaglandins and leukotrienes are the best studied.
Another important function of polyunsaturated fatty acids is that they are vital components of brain tissue and other nerves. The omega-3 fatty acid, docosahexaenoic acid (DHA), is particularly important. A normal adult brain contains more than 20 grams of DHA!
Fat fish is the primary source of marine omega-3
Research among native Greenlanders in the early 1970s opened the eyes of the medical and nutritional world to the importance of a "new" dietary factor: marine omega-3 fatty acids.
One of the first countries to start performing significant research along these lines was Japan. Unlike the diet in Greenland, the Japanese diet is low in fat. Similar to the diet in Greenland, however, the Japanese diet has a relatively large proportion of fish and seafood. Consequently, it is high in marine omega-3. The incidence of cardiovascular disease is very low, making Japan among the world leaders in terms of life expectancy.
The acceptance of marine omega-3 fatty acids as benefiting health in general is increasing worldwide. As a result, products containing omega-3 fatty acids are registered as pharmaceuticals or natural medicines in a number of countries.
WIN markets and sells its Omega-3 product as a supplement, not as a drug. But also note that the FDA itself has approved a qualified health claim about the constituents of Omega-3, and a reduced risk of heart disease. Please see below.
Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease. One serving of WINOmeg3complex provides 1400mg of EPA and DHA omega-3 fatty acids.
Marine Omega-3 Oils and the Health Authorities
Generally, a daily intake of 0.6 - 1 grams of omega-3 fatty acids in the form of EPA and DHA is recommended as a dietary supplement. Based on views expressed by international experts at a recent meeting in Washington, D.C., this recommendation confirms an adequate intake of the various fatty acids.
Why do we need EPA and DHA?
Healthy adults have a certain ability to metabolize alpha-linolenic acid to EPA and DHA. Babies do not have this ability and are entirely dependent on receiving these essential elements through what they eat. The ability to metabolize EPA and DHA may also be reduced in elderly people.
Omega-3 and the medical profession
Research into the biological and clinical effects of marine omega-3 fatty acids was originally initiated by physicians. The medical profession is still working to learn more about the importance of essential fatty acids for a healthy life.* To date, clinical research has resulted in more than 6,000 scientific publications worldwide, and the research continues.
Several thousand patients and healthy people have used the product since mid-80’s meaning that the concentrates are very well documented regarding safety. A special issue on safety has been published in a medical journal (1).
1) Schmidt EB, et al. Safety aspects of Fish Oils. Experiences with an omega-3 concentrate of re-esterified triglycerides. Drug Invest. 1994;7(4):215-220
WINOmeg3complex has met all of the standards required to be listed in the Physicians' Desk Reference, and independent 3rd party certificates of analysis are available by batch.
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Rheumatic arthritis is a chronic disease of the synovial tissue in the joints, leading to inflammation and eventually to permanent deformation. The synovia normally produces joint fluid, which acts as a lubricant, also providing the cartilage with important nutrients. In rheumatoid arthritis, the synovia are invaded by activated white blood cells, releasing certain chemical substances into the fluid and leading to the degeneration of cartilage and subsequent inflammation of the surrounding tissue. The symptoms are pain, stiffness, reduction of joint and muscle strength and, ultimately, joint deformation.
Today's treatment of rheumatic disease is directed toward suppressing symptoms and preventing joint deformation. Medical treatment is characterized by an aggressive approach, combining non-steroidal anti-inflammatory drugs (NSAIDs) with cytostatics or other immune-suppressants. The goal of this aggressive treatment is to improve the patient's long-term outcome with respect to symptoms and function. However, the challenge is to prevent adverse effects while monitoring liver and bone marrow function.
Omega-3 fatty acids not only reduce symptoms and may potentially facilitate lower doses of NSAIDs, they also appear to preserve joint function, meaning they act as drug-disease-modifiers. To take optimal advantage of the beneficial effects of omega-3 fatty acids, individuals must take large doses, larger quantities than what is possible to get through diet alone. This requires dietary supplements of concentrated omega-3 fatty acids, 5-6 grams per day.
Diet can interfere with the clinical course of a disease since fatty acids help fine-tune the human immune system. omega-3 fatty acids reduce immunological effects while omega-6 fatty acids have the opposite effect. Besides eating a diet rich in fish containing omega-3 fatty acids and/or taking dietary supplements, individuals with rheumatism should eat a diet low in red meat and avoid using vegetable oils rich in omega-6 fatty acids, such as soy, corn and sunflower oil. Use olive oil and rapeseed oil instead because they contain more Omega-9 fatty acids, which do not increase immune functions.
Several controlled clinical studies have shown significant symptom relief from taking high doses of omega-3 fatty acids for a period of at least 2 to 3 months. Furthermore, intake of omega-3 fatty acids reduced the need for NSAIDs, which is important to prevent adverse effects from the gastro-intestinal tract. A summary of the most important studies has been published in the Journal of Clinical Epidemiology. (1)
One interesting and very important observation was made by a Danish doctor working on the Faeroe Islands and in Greenland. Upon X-raying patients with rheumatoid arthritis (Personal communication), he found their joints to be normal or almost normal even when they had had the disease for 10 years or more. This result would have been very different in a Danish population where joint deformation increases in direct proportion to time.
Rheumatic arthritis is an auto-immune disease, affecting about 1% of the population in western countries. The mechanism underlying the development of auto-immune diseases such as rheumatoid arthritis is not completely understood. Most certainly, it involves a combination of genetic and environmental factors, but psychological factors may also be involved. The coastal population of Japan has a high incidence of a genetic configuration, which is often accompanied by rheumatic diseases (so-called HLA-D4). However, rheumatoid arthritis rarely occurs in Japan, probably due to the high intake of fish and thereby omega-3 fatty acids in the Japanese diet. (1) Fortin PR et al. Validation of a meta-analysis: the effects of fish oil in rheumatoid arthritis. J Clin Epidemiol 1995;48:1379-1390.
Essential fatty acids (EFAs) are connected with visual development in infants. Deficiencies in adults (particularly omega-3) can lead to impaired vision, and studies suggest that prolonged deficiencies might lead to retinal/macular damage. A study published in the August 2001 issue of Archives of Ophthalmology found that omega-6 fatty acids were associated with an increased risk of advanced macular degeneration, but that omega-3 fatty acids protected against it (as long as LA intake was low). Meanwhile, a 2003 study found omega-3 to decrease your risk of developing dry eye syndrome, and other studies have found that LA and gamma-linolenic acid (GLA) improve dry eye symptoms.
The body converts both types of EFAs into prostaglandins, whose functions include helping the eye's aqueous humor to drain and regulating intraocular pressure.
Research shows that omega-3 fatty acids reduce blood lipids, blood pressure and blood clotting, and help prevent atherosclerosis and cardiac arrhythmia. omega-3 fatty acids are mainly found in fatty fish. These include sardines, mackerel, herring and salmon. To help prevent heart attack, increase your intake of omega-3 fatty acids by eating more fish or taking a high-quality omega-3 supplement. About 1 to 2 grams of omega-3 fatty acids per day is the dose that doctors recommend to prevent heart disease. You can get that much by eating fatty fish 2-4 times per week, or you can take omega-3 supplements.
In the past 20 years, the United States has provided millions of dollars in funding to major universities and research facilities to study omega-3's heart-healthy benefits. While the initial focus was on reducing elevated levels of LDL, triglycerides, and VLDL,” all long known by the medical community to be a major cause of arteriosclerosis and hypertension, meanwhile increasing levels of valuable HDL” researchers have found that without a sufficient supply of omega-3s, the body will use saturated fat (omega-6) to construct cell membranes. This is bad news as cell membranes are less elastic, a situation that can have a negative effect on the heart because it makes it harder to return to a resting state.
2-4 grams per day can balance the risk factors.If you have had a heart attack or you have risk factors such as hypertension, diabetes, elevated blood lipids (particularly triglycerides), or if you are a smoker, you will benefit from taking omega-3 fatty acid supplements, but the dose should be doubled to 2 to 4 grams per day. In an English study (1), half the heart attack patients were advised to increase the intake of fatty fish or take omega-3 supplements upon leaving the hospital, while the rest were given no such advice. The difference in mortality was significant after just three months and the positive effect of supplementation persisted in subsequent years.
(1) Burr ML et al. The Lancet 1989;241:757-761
Women in the western world are exhibiting a tendency not to carry their babies to term. This may be due to an insufficient intake of omega-3 fatty acids. Pregnant women should eat a lot of fish and/or take an omega-3 supplement. Omega-3 fatty acids can help bring pregnancies to term!
It would seem prudent for an expectant mother to eat more fish, especially during the last trimester of her pregnancy, or to take an omega-3 dietary supplement every day. The Danish studies were based on a daily dose of 4 grams of Pikasol containing a total of 2.4 grams of omega-3 fatty acids. Women should continue this regimen for as long as they breast feed. If they choose not to provide their babies with nature's most perfect food – breast milk – they should use an infant formula fortified with omega-3 fatty acids.
* Olsen SF et al. Randomized controlled trial of effect of fish-oil supplementation on pregnancy duration. The Lancet 1992;339:1003-1007 ** Personal communication; article in progress.
Premature infants run a high risk of spending their first months of life in hospital. The handicap of being born prematurely may even persist throughout their lifetimes. When, in addition to struggling with prematurely, these children are given infant formula without omega-3 fatty acids, they risk permanent reductions in their mental and visual development. It has also been shown that individuals born prematurely are more prone to develop hypertension later in life, and insufficiently treated hypertension is a risk factor for the premature development of coronary heart disease. (Siewert-delle A. Long term renal function in primary hypertension. Acad. thesis University of Gothenburg 1998).
Made from fish oil from fisheries of the South American coast, WINOmeg3complex is the ideal natural supplement for production of Omega-3 fatty acids. WINOmeg3complex is one of the most concentrated pharmaceutical-grade products available today (at 85%). It is among the highest ratios of EPA and DHA on the market.
The health benefits involved in the consumption Omega-3 acids are absolutely astonishing. WINOmeg3complex aids healthy and flexible joints, cognitive clarity, digestion, reduction of inflammation throughout the body, prevention of blood clots, and even helps to curb depression. DHA is the most abundant omega-3 acid in the brain and EPA strengthens the immune system.
While simply eating more fish would seem to be a healthy option, many wild species of large fish are polluted with dangerous toxins such as mercury. WINOmeg3complex is made from fish on the bottom of the food chain, which naturally contain higher levels of Omega-3 acids and lower levels of toxins.
What makes WINOmeg3complex tower above other fish oil supplements is it's quality and freshness. It does not smell fishy, which is an indication of exposure to oxygen. WINOmeg3complex is manufactured in a nitrogen environment and is not exposed to air once in capsules. WINOmeg3complex™ has a high ratio of EPA to DHA (3.3:1) and is a pharmaceutical-grade oil with more than 85% omega-3 fatty acids.
is a safe alternative with no drug-like side effects. For best results, it is recommended to decrease consumption of saturated and trans fatty acids found in processed and fast foods.